If you have any doubt whatsoever as to whether or not your guinea pig needs to be seen by a vet, then the answer is "Yes, you do need to see a vet", sometimes ASAP if the situation is an emergency.
Guinea pigs are like any other living species whether two-legged or four-legged. All areas of the body can have problems or concerns that need to be evaluated, in the case of guinea pigs, by a qualified exotics vet who regularly and successfully treats guinea pigs. Below are some examples of symptoms that would or could require a visit to the vet.
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